It can range from feeling nothing, or very little, to moderate discomfort for 1-2 seconds as the marrow is being aspirated. I have had three and the most I can say is that I had some muscle soreness for a few days after the first one. It is far more important to know what is going on in your marrow, as it may dictate a change in treatment. In comparison to the battle we are fighting, I do not see it as anything to be concerned about submitting to.

Hey there...A bone marrow is deffinately needed to see if it has gone there because the treatment is an additional step added to treat bone marrow. I also have the same dx. Cure rate is very good but not if they don't check your bone marrow. I have had 2 marror tests and all with no sedation. They will sedate you if you ask early before your appt. is actually upon you. Several people I know have had sedation. Thinking about it I guess I would ask for it if there is a next time! Keep us posted Good Luck!

Hey there, good question for a very necessary procedure. If you are concerned about possible pain ask for light sedation, (which actually takes longer to do than the actual BM bio) I have light sedation because I have very dense ones in the area they take the samples from. I have had five in the past three years. Because I had a small % in my bone and I am doing W&W we are keeping an eye on it. Oddly enough I went to 0% on my fourth one but by the 5th one it had returned, but again, less than 4%. They will not even treat until I get to 30% as long as I have no other nodes involved.
You said your DX was large B cell, did they give you a subtype such as Diffused large B cell? Are you having any B Symptoms and do you know what node areas are involved from your scans? All this makes a difference on treatment decisions. If it is Diffused, there are very good cure rates as it responds quickly to treatment.

You need to do this BM test, just ask for the light sedation, they don't care either way, and it will make you worry less. Remember through all of this you need to be your best advocate, if you hurt tell them, if you fill sick tell them, not that you will so don't assume anything, but defiantly speak up for yourself. We are here for you anytime,
Welcome hugs, KB

Good luck, Friday on the BM bio. Anger is a normal reaction, so this is a good place to vent and gain some type of perspective on it all. Once you get your treatment going you will have something to apply that anger towards and that will help, then you will be ale to also have a sense of regaining control over your life, and a future. We all changed and are still changing, give yourself time to adjust and be kind to yourself. The stress of all this is huge so rest when you can and surround yourself with as much positive stuff and people as you can vs. negative and people who want to share cancer horror stories with you. They don't help.
Take care and let us know how you are doing,
Hugs, kb